Isocitrate Dehydrogenase

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 VAL-134   ASN-135  8.1 7.9 21.6 -8.7 75.1 78.2 57.1
 ASN-135   PRO-136  5.8 5.4 13.2 -13.2 131.3 138.5 -16.3
 PRO-136   VAL-137  4.9 4.4 9.3 -16.3 110.0 105.9 11.6
 VAL-137   LEU-138  3.1 3.5 31.5 -39.9 44.7 46.6 -48.0
 LEU-138   ARG-139  2.8 2.9 11.4 -6.5 72.5 73.9 26.3
 ARG-139   GLU-140  1.0 0.9 -6.6 4.7 53.8 53.3 22.4
 GLU-140   GLY-141  3.4 3.6 -14.5 10.4 127.8 126.2 -19.6

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 MET-565   LEU-566  5.0 4.0 -2.6 -2.5 130.4 133.8 -27.8
 LEU-566   SER-567  2.5 2.1 1.3 4.8 22.5 26.6 32.1
 SER-567   ILE-568  2.6 2.4 -17.3 14.2 120.3 118.2 -3.4
 ILE-568   VAL-569  3.1 3.5 -2.6 -3.7 155.0 156.2 -42.8
 VAL-569   PRO-570  3.8 4.3 -5.9 2.9 106.8 105.8 -22.8
 PRO-570   LEU-571  7.3 7.8 -3.1 4.4 173.8 175.0 10.7
 LEU-571   MET-572  7.0 7.4 -1.2 14.2 114.8 114.7 58.2

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees