Beta-Adrenergic Receptor Kinase 1

(All numbering and residues are taken from first PDB file)

Bending Residue Dihedral Analysis

Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASN-183   ILE-184  8.2 8.3 3.6 13.7 169.9 173.2 -226.5
 ILE-184   HIS-185  7.7 7.5 19.4 -23.1 132.8 113.7 231.4
 HIS-185   LEU-186  10.5 10.6 -52.0 49.6 35.3 18.0 48.9
 LEU-186   THR-187  10.5 9.8 0.9 1.9 127.8 125.5 -69.3

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ASP-212   THR-213  9.4 9.7 1.7 -23.5 88.3 85.8 160.2
 THR-213   GLY-214  9.2 9.5 26.7 -9.8 25.1 27.0 168.8
 GLY-214   LYS-215  9.2 9.4 -51.3 46.4 105.1 106.3 -182.7
 LYS-215   MET-216  6.6 6.4 -29.6 24.1 35.5 28.6 15.1
 LYS-215   MET-216  6.6 6.4 -29.6 24.1 35.5 28.6 15.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 LYS-215   MET-216  6.6 6.4 -29.6 24.1 35.5 28.6 15.1
 LYS-215   MET-216  6.6 6.4 -29.6 24.1 35.5 28.6 15.1
 MET-216   TYR-217  4.9 5.3 13.2 -16.0 79.7 81.2 95.5
 TYR-217   ALA-218  1.2 1.5 4.6 -13.9 141.9 140.6 97.4

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-254   VAL-255  13.6 13.7 4.3 -17.9 86.5 90.9 41.2
 VAL-255   CYS-256  10.3 10.3 -2.9 0.6 18.6 31.2 73.5
 CYS-256   MET-257  9.1 9.4 30.5 -22.7 107.5 97.6 -14.8
 MET-257   SER-258  7.5 7.3 8.1 11.2 138.8 144.3 -210.7
 SER-258   TYR-259  4.4 4.4 0.0 5.6 64.7 67.0 126.2
 TYR-259   ALA-260  5.5 5.6 10.8 -21.1 61.3 59.3 -13.1

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees


Residue
i
Residue
i+1
Distance of hinge axis to residue i in conformer 1
(A)
Distance of hinge axis to residue i in conformer 2
(A)
Change in psi (i)
(deg)
Change in phi (i+1)
(deg)
Angle of psi(i) axis to hinge axis conformer 1
(deg)
Angle of psi(i) axis to hinge axis conformer 2
(deg)
Percentage Progress
 ILE-513   SER-514  6.3 5.8 3.7 -18.7 113.7 115.7 93.9
 SER-514   GLU-515  4.5 4.1 24.5 -19.2 67.2 68.4 67.5
 GLU-515   ARG-516  6.5 6.6 17.1 -19.5 31.9 34.5 -123.9

Downloading Image

Graph shows rotational transition at bending residues and can be used to identify hinge bending residues.
Probably only informative for interdomain rotations greater than 20 degrees