DynDom - Protein Domain Motions

Glycogen [Starch] Synthase Isoform 2

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Glycogen [Starch] Synthase Isoform 2
Conformer 1 (PDB)	3nb0 (A)
Conformer 2 (PDB)	3naz (A)
Window Length	9
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	239	0.59	201 - 203 285 - 380 430 - 504 512 - 525 534 - 534 536 - 538 546 - 553 556 - 594
2	320	0.5	6 - 200 204 - 270 505 - 511 526 - 533 535 - 535 539 - 540 554 - 555 595 - 634
3	36	1.03	381 - 429

Sequence

`________________________________________________________________________________________________________________________` `3nb0(A) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `:` `3naz(A) : SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNKATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAPKVILFDLDSVRGYSNEWKGD` `________________________________________________________________________________________________________________________` `____________________________________________________________________________200_________________________________________` `3nb0(A) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `:` `3naz(A) : LWSLVGIPSPENDFETNDAILLGYTVAWFLGEVAHLDSQHAIVAHFHEWLAGVALPLCRKRRIDVVTIFTTHATLLGRYLCASG--dFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSA` `____________________________________________________________________________200_________________________________________` `__________________________270___________________________________________________________________________________________` `3nb0(A) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `:` `3naz(A) : DVFTTVSQITAFEAEHLLKRKPDGILPNGLNVIKFQ-------lHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTVVAFIVMPAKN` `__________________________270___________________________________________________________________________________________` `_______________379_______________________________________________429____________________________________________________` `3nb0(A) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYPHNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `:` `3naz(A) : NSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYP-------------eLLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDANDLILNKIRQVQLFNSPSDRVKMIFHPEFL` `_______________379_______________________________________________429____________________________________________________` `____________________504____511___________525_____533_________________553______________________________________594_______` `3nb0(A) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNATEALSDLLDWKR` `:` `3naz(A) : NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDL-----aKDYGIYIVDRRFKAPDESVEQLVDYMEEFVKKTAAQAINQRNRTERLSDLLDWKR` `____________________504____511___________525_____533_________________553______________________________________594_______` `______________________________________` `3nb0(A) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA` `:` `3naz(A) : MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA` `______________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	4.9
Translation (A)	-0.1
Closure (%)	24.1
Bending Residues ( green )	200 - 201 203 - 204 270 - 288 504 - 505 511 - 512 525 - 526 533 - 546 553 - 556 594 - 595
Bending Region Analysis

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( yellow )	3
Rotation Angle (deg)	13.6
Translation (A)	-0.1
Closure (%)	94.4
Bending Residues ( green )	379 - 381 429 - 430
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Shear

Conformer 1 Contact:
Residue 1 ———› Residue 3

Conformer 2 Contact:
Residue 3 ———› Residue 1

Movement classification:

No Contacts

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