DynDom - Protein Domain Motions

Nuclear Valosin-Containing Protein-Like

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Nuclear Valosin-Containing Protein-Like
Conformer 1 (PDB)	2x8a (A)
Conformer 2 (PDB)	3cf2 (A)
Window Length	9
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	21	6.25	776 - 796
2	20	6.29	634 - 645 677 - 684

Sequence

`________________________________________________________________________________________________________________________` `2x8a(A) : ********************************************************IGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVANESGLNFI` `:` `3cf2(A) : NRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFL` `________________________________________________________________________________________________________________________` `_____________________________________684________________________________________________________________________________` `2x8a(A) : SVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPsVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKTITKNGTKPPLDAD` `:` `3cf2(A) : EAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHC--EGEPIKREDEEESLNEVGYDDIGG-CRKQLAQIKEMVELPLRHPALF-----KAIGVKPPRGILLYGPPGTGKT` `_____________________________________180________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2x8a(A) : VNLEAIAGDLRCDCYTGADLSALVREASICALRQEMlKVSHKHFEEAFKKVRSSI*************************************************************` `:` `3cf2(A) : LIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIP` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2x8a(A) : ********************************************************************************************************************` `:` `3cf2(A) : DATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQEL` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `2x8a(A) : ********************************************************************************************************************` `:` `3cf2(A) : VQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIaDRVINQILTEMDGMSTKKNVFIIGAnRPD` `________________________________________________________________________________________________________________________` `___________________________________________________________________` `2x8a(A) : *****************************************************************` `:` `3cf2(A) : IIDPAILRPGRLDQLIYIkSRVAILKANLRKSaKDdLTEICQRACKLAIRESIEvPEhFEEAMeMFA` `___________________________________________________________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	156.3
Translation (A)	-14.2
Closure (%)	97.8
Bending Residues ( green )	684 - 776
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification:

No Contacts

PyMOL Script

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