DynDom - Protein Domain Motions

S-Arrestin

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	S-Arrestin
Conformer 1 (PDB)	7jsm (B)
Conformer 2 (PDB)	4j2q (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	173	2.44	12 - 176 179 - 188 296 - 298 320 - 320 322 - 323
2	163	2.65	177 - 178 189 - 295 299 - 319 321 - 321 324 - 358

Sequence

`________________________________________________________________________________________________________________________` `7jsm(B) : PNHVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDIDVMGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLP` `:` `4j2q(A) : HVIFKKISRDKSVTIYLGKRDYIDHVERVEPVDGVVLVDPELVKGKRVYVSLTCAFRYGQEDID-mGLSFRRDLYFSQVQVFPPVGASGATTRLQESLIKKLGANTYPFLLTFPDYLP` `________________________________________________________________________________________________________________________` `______________________________________________176_____184_______________________________________________________________` `7jsm(B) : CSVMLQPAPQDVGKSCGVDFEIKAFATHSTDVEEDKIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNV` `:` `4j2q(A) : CSVMLQPAPQDVGKSCGVDFEIKAFATH-------kIPKKSSVRLLIRKVQHAPRDMGPQPRAEASWQFFMSDKPLRLAVSLSKEIYYHGEPIPVTVAVTNSTEKTVKKIKVLVEQVTNV` `______________________________________________176_____184_______________________________________________________________` `_____________________________________________295____________________318_________________________________________________` `7jsm(B) : VLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGLeLTSSEVATEVPFRLMHPQPEDeNFVFEE` `:` `4j2q(A) : VLYSSDYYIKTVAAEEAQEKVPPNSSLTKTLTLVPLLANNRERRGIALDGKIKHEDTNLASSTIIKEGIDKTVMGILVSYQIKVKLTVSGL-lTSSEVATEVPFRLMHPQP*****` `_____________________________________________295____________________318_________________________________________________` `_______________________` `7jsm(B) : FARQNLKDAGEYKEEKTDQEAAM` `:` `4j2q(A) : *********************` `_______________________`

Morph

This morph was created using the MorphIt_Pro protein morphing technique.
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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	19.5
Translation (A)	-1.9
Closure (%)	60.7
Bending Residues ( green )	176 - 179 184 - 190 295 - 302 318 - 324
Bending Region Analysis

Dynamic Contact Graph

Conformer 1 Contact:
Residue 1 ———› Residue 2

Conformer 2 Contact:
Residue 2 ———› Residue 1

Movement classification: Hinge

PyMOL Script

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