DynDom - Protein Domain Motions

Succinate Dehydrogenase [Ubiquinone] Flavoprotein Subunit, Mitochondrial

(All numbering and residues are taken from first PDB file)

Run Details Domains Sequence Morph Domain Pairs Contact Graph

DynDom run details

Property	Value
Name	Succinate Dehydrogenase [Ubiquinone] Flavoprotein Subunit, Mitochondrial
Conformer 1 (PDB)	3sfd (A)
Conformer 2 (PDB)	6c12 (A)
Window Length	5
Minimum ratio	1.0
Minimum domain size	20

Domains

Domain	Size	Backbone RMSD (A)	Residues
1	399	5.58	13 - 252 364 - 483 485 - 579
2	112	1.4	253 - 363 484 - 484

Sequence

`________________________________________________________________________________________________________________________` `3sfd(A) : STQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQR` `:` `6c12(A) : MKLPV--REFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQG----------------hMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPF-----------` `________________________________________________________________________________________________________________________` `________________________________________________________________________________________________________________________` `3sfd(A) :` `AFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLM-ENGECRGVIALCIEDGSIHRIRARNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDL` `:` `6c12(A) :` `---------------------aDRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDM` `________________________________________________________________________________________________________________________` `_252_____________________________________________________________________________________________________________363____` `3sfd(A) : EFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGC-GPEKDHVYLQLHHLPPEQLAVRLPGISETAMIFAGVDVTKEPIPVLPTVHYN` `:` `6c12(A) : EMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYM` `_240_____________________________________________________________________________________________________________352____` `________________________________________________________________________________________________________________________` `3sfd(A) : MGGIPTNYKGQVLRHVN--GQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESV-MNLDKLRFANGTIRTSE----LRLSMQKSMQSH` `:` `6c12(A) : MGGIPTKVTGQALT-VNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALR----DASESDVEASLDRLNRWNNN-RNGEDPVAIRKALQECMQHN` `________________________________________________________________________________________________________________________` `483_____________________________________________________________________________________________________________________` `3sfd(A) : AAVFRVGSVLQEGCEKILRLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERVDEYDYSKPIQGQQKKPFQEHWRKHTLSYVDVKTGKVSLEYR` `:` `6c12(A) : FSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPP****` `473_____________________________________________________________________________________________________________________` `______________________` `3sfd(A) : PVIDKTLNEADCATVPPAIRSY` `:` `6c12(A) : ********************` `______________________`

Morph

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Status: Initialising

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Domain Pairs

Property	Value
Fixed Domain ( blue )	1
Moving Domain ( red )	2
Rotation Angle (deg)	39.8
Translation (A)	1.0
Closure (%)	87.4
Bending Residues ( green )	252 - 253 363 - 364 483 - 485
Bending Region Analysis

Dynamic Contact Graph

The dynamic contact graph is still being generated. Progress: Initialising

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